Despair is a minion of Vadriel and Omega. Referred to as "brother" by Doom, Despair is a small demon creature with full flesh. He is one of the most loyal, if not the most, to Omega and Vadriel. Humorously, he is almost always hungry. He helped with the takeover in 4000. Despair was the only one of Omega and Vadriel's minions that survived. He was killed after Omega died.
- "I am Despair, here to rip your flesh out! Later, can I eat it though?"
- "Yes Master. Ehem, I mean Masters."